In this work, we present a neuromorphic system that combines for the first time a neural recording headstage with a signal-to-spike conversion circuit and a multi-core spiking neural network (SNN) architecture on the same die for recording, processing, and detecting High Frequency Oscillations (HFO), which are biomarkers for the epileptogenic zone. The device was fabricated using a standard 0.18$\mu$m CMOS technology node and has a total area of 99mm$^{2}$. We demonstrate its application to HFO detection in the iEEG recorded from 9 patients with temporal lobe epilepsy who subsequently underwent epilepsy surgery. The total average power consumption of the chip during the detection task was 614.3$\mu$W. We show how the neuromorphic system can reliably detect HFOs: the system predicts postsurgical seizure outcome with state-of-the-art accuracy, specificity and sensitivity (78%, 100%, and 33% respectively). This is the first feasibility study towards identifying relevant features in intracranial human data in real-time, on-chip, using event-based processors and spiking neural networks. By providing "neuromorphic intelligence" to neural recording circuits the approach proposed will pave the way for the development of systems that can detect HFO areas directly in the operation room and improve the seizure outcome of epilepsy surgery.

Artificial Intelligence is playing an ever increasing role in the lives of civilized nations, though most citizens probably don't realize it. It's now commonplace to speak with a computer when calling a business. Facebook is becoming scary accurate at recognizing faces in uploaded photos. Physical interaction with smart phones is becoming a thing of the past… with Apple's Siri and Google Speech, it's slowly but surely becoming easier to simply talk to your phone and tell it what to do than typing or touching an icon. Try this if you haven't before -- if you have an Android phone, say "OK Google", followed by "Lumos".

We present test results from spike-timing correlation learning experiments carried out with silicon neurons with STDP (Spike Timing Dependent Plasticity) synapses. The weight change scheme of the STDP synapses can be set to either weight-independent or weight-dependent mode. We present results that characterise the learning window implemented for both modes of operation. When presented with spike trains with different types of synchronisation the neurons develop bimodal weight distributions. We also show that a 2-layered network of silicon spiking neurons with STDP synapses can perform hierarchical synchrony detection.

We present test results from spike-timing correlation learning experiments carried out with silicon neurons with STDP (Spike Timing Dependent Plasticity) synapses. The weight change scheme of the STDP synapses can be set to either weight-independent or weight-dependent mode. We present results that characterise the learning window implemented for both modes of operation. When presented with spike trains with different types of synchronisation the neurons develop bimodal weight distributions. We also show that a 2-layered network of silicon spiking neurons with STDP synapses can perform hierarchical synchrony detection.

The weight change scheme of the STDP synapses can be set to either weight-independent or weight-dependent mode. We present results that characterise the learning window implemented for both modes of operation. When presented with spike trains with different types of synchronisation the neurons develop bimodal weight distributions. We also show that a 2-layered network of silicon spiking neurons with STDP synapses can perform hierarchical synchrony detection.

We have developed a VLSI silicon neuron and a corresponding mathematical model that is a two state-variable system. We describe the circuit implementation and compare the behaviors observed in the silicon neuron and the mathematical model. We also perform bifurcation analysis of the mathematical model by varying the externally applied current and show that the behaviors exhibited by the silicon neuron under corresponding conditions are in good agreement to those predicted by the bifurcation analysis.

We have developed a VLSI silicon neuron and a corresponding mathematical model that is a two state-variable system. We describe the circuit implementation and compare the behaviors observed in the silicon neuron and the mathematical model. We also perform bifurcation analysis of the mathematical model by varying the externally applied current and show that the behaviors exhibited by the silicon neuron under corresponding conditions are in good agreement to those predicted by the bifurcation analysis.

We have developed a VLSI silicon neuron and a corresponding mathematical modelthat is a two state-variable system. We describe the circuit implementation and compare the behaviors observed in the silicon neuron and the mathematical model. We also perform bifurcation analysis ofthe mathematical model by varying the externally applied current and show that the behaviors exhibited by the silicon neuron under corresponding conditionsare in good agreement to those predicted by the bifurcation analysis.